SCHEMBL9748667

SCHEMBL9748667

C=CCN(CCCCC)c1ccc(C=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
ALDH1A3 P47895 4/20 0.54
ALDH3A1 P30838 3/20 0.54
CYP2A6 P11509 1/20 0.41
CYP2A13 Q16696 1/20 0.41
CNR2 P34972 5/20 0.37
KCNH2 Q12809 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
CRHBP P24387 1/20 0.36
CYP2C19 P33261 1/20 0.36
CRHR2 Q13324 1/20 0.36
AR P10275 1/20 0.36
CNR1 P21554 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9879754 0.98 ALDH1A1 (0.53) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL6843923 0.89 CNR2 (0.37) ALDH1A1ALDH1A3ALDH3A1CNR2KCNH2
SCHEMBL1825440 0.87 CHKA (0.38) CNR2KCNH2CNR1CHRM2CHRM4
SCHEMBL4003205 0.87 ALDH1A1 (0.66) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL26836706 0.85 ALDH1A1 (0.63) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL10438443 0.85 ALDH1A3 (0.63) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL609500 0.85 ALDH1A3 (0.63) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL9875023 0.85 ALDH1A3 (0.63) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL9448811 0.85 ALDH1A3 (0.63) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL1166127 0.85 ALDH1A3 (0.63) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301411-B1 FILM COMPOSED OF AT LEAST ONE MONOMOLECULAR LAYER HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-15 EP disclosed
EP-0301411-A1 Film composed of at least one monomolecular layer HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-01 EP disclosed