Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 20/20 | 0.72 |
| ▸ | BCHE | P06276 | 16/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 13/20 | 0.63 |
| ▸ | GRIN2A | Q12879 | 13/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29817910 | 0.84 | BCHE (1.00) | ACHEBCHE | |
| SCHEMBL30411706 | 0.80 | ACHE (0.63) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| Tacrine SCHEMBL8003897 | 0.79 | ACHE (0.82) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL24931057 | 0.78 | MAPT (0.77) | — | |
| SCHEMBL5990879 | 0.78 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL29817805 | 0.77 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9823028 | 0.76 | KMT2A (0.51) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL29817798 | 0.76 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9258833 | 0.76 | ACHE (0.69) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL31303907 | 0.76 | MAPT (0.64) | ACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175172-A | Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients | DIETLIN FRANCOIS (FR) | 1992-12-29 | — | — | US | disclosed |