Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242261 | 0.75 | KCNA5 (0.61) | CYP26A1CYP3A4CYP19A1MAPTCYP17A1 | |
| SCHEMBL11706076 | 0.74 | CYP17A1 (0.67) | CYP26A1CYP3A4HMOX1CYP19A1CYP11B1 | |
| SCHEMBL1507977 | 0.72 | CYP19A1 (0.51) | CYP26A1CYP3A4CYP19A1 | |
| SCHEMBL31185800 | 0.70 | CYP26A1 (0.57) | CYP26A1CYP3A4HMOX1CYP19A1CYP11B1 | |
| SCHEMBL9784363 | 0.70 | CYP17A1 (0.67) | CYP26A1CYP3A4HMOX1CYP19A1CYP11B1 | |
| SCHEMBL29178598 | 0.70 | CYP19A1 (0.56) | CYP26A1CYP3A4HMOX1CYP19A1CYP11B1 | |
| SCHEMBL9859794 | 0.69 | LTA4H (0.48) | MAPT | |
| SCHEMBL2823983 | 0.69 | CYP19A1 (0.56) | CYP26A1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27651636 | 0.68 | CYP3A4 (0.70) | CYP3A4HMOX1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11155623 | 0.68 | HMOX1 (0.57) | CYP26A1CYP3A4HMOX1CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100890-A | Antidepressants, Fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0218118-B1 | ARYLMETHYL AZOLES AND THEIR SALTS, METHOD FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| US-5023357-A | Arylmethylazole preparation processes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |
| US-4876354-A | FUNGICIDES, ANTIDEPRESSANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| EP-0218118-A1 | Arylmethyl azoles and their salts, method for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-15 | — | — | EP | disclosed |