Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20604139 | 0.80 | IKBKB (0.44) | TSHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL9749076 | 0.80 | ADORA3 (0.43) | KMT2AMEN1PRNPKDM4EMAPT | |
| SCHEMBL28026247 | 0.79 | TSHR (0.54) | TSHRKMT2AMEN1PRNPMAPK1 | |
| SCHEMBL12970520 | 0.79 | PDE10A (0.47) | KMT2AMEN1MAPK1L3MBTL1KDM4E | |
| SCHEMBL15662044 | 0.78 | CYP1A2 (0.42) | TSHRMAPK1KDM4EJAK2JAK3 | |
| SCHEMBL9747984 | 0.77 | MEN1 (0.42) | KMT2AMEN1PRNPKDM4EMAPT | |
| SCHEMBL9748942 | 0.77 | KDM4E (0.43) | TSHRKMT2AMEN1PRNPL3MBTL1 | |
| SCHEMBL2921221 | 0.77 | JAK2 (0.57) | TSHRKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL15661115 | 0.77 | HSD17B10 (0.50) | TSHRKMT2AMAPK1KDM4EMAPT | |
| SCHEMBL6928259 | 0.76 | CDC25B (0.54) | TSHRKMT2AMEN1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224842-B1 | PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |