Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747984 | 0.86 | MEN1 (0.42) | ADORA3KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9748942 | 0.86 | KDM4E (0.43) | ADORA3KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9748885 | 0.84 | KDM4E (0.39) | ADORA3KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10921204 | 0.81 | CA12 (0.42) | ADORA3KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10924140 | 0.80 | PDE4D (0.43) | ADORA3KDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10928314 | 0.80 | CA12 (0.41) | ADORA3KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9749174 | 0.80 | TSHR (0.45) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10919570 | 0.80 | LMNA (0.47) | ADORA3KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9749658 | 0.78 | POLB (0.37) | ADORA3KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10514354 | 0.76 | PDE4D (0.40) | ADORA3KDM4ESMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224842-B1 | PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |