Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614851 | 0.85 | LDHA (0.46) | LDHACYP1A1CYP1B1 | |
| SCHEMBL9749492 | 0.83 | PPARG (0.46) | LDHA | |
| SCHEMBL10915187 | 0.79 | — | — | |
| SCHEMBL17693398 | 0.78 | MAPK1 (0.44) | CA2MAPK1 | |
| SCHEMBL9748816 | 0.78 | TDP1 (0.49) | MAPK1 | |
| SCHEMBL27926016 | 0.77 | CYP1A2 (0.60) | MAPK1LDHACYP1A1CYP1B1 | |
| SCHEMBL1203591 | 0.77 | — | — | |
| SCHEMBL2005766 | 0.75 | TYR (0.51) | — | |
| SCHEMBL9749184 | 0.75 | CYP1A2 (0.57) | MAPK1LDHACYP1A1CYP1B1 | |
| SCHEMBL9614838 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201071-B1 | 2-SUBSTITUTED-1-NAPHTHOLS AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-03-04 | — | — | EP | claimed |