SCHEMBL9749271

SCHEMBL9749271

FC(F)(F)c1nc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.32
ENPP1 P22413 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10858879 0.86 ENPP1 (0.34) ENPP3ENPP1
SCHEMBL10860900 0.80 NOTUM (0.30) ENPP3ENPP1
SCHEMBL10704444 0.77 ALDH1A1 (0.33) ENPP3ENPP1
SCHEMBL1377623 0.76
SCHEMBL2573734 0.73 KDM4E (0.33)
SCHEMBL6718305 0.73 LMNA (0.31)
SCHEMBL9749688 0.73
SCHEMBL9749216 0.73
SCHEMBL9815388 0.71 GLP1R (0.42)
SCHEMBL468366 0.69 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5087699-A Chemical intermediate for pyridinethiolate nickel complex; light stabilizers, infrared absorbers and chelate compounds RICOH COMPANY, LTD. (JP) 1992-02-11 US disclosed