Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425974 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9749297 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9749310 | 0.89 | LMNA (0.41) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9750404 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9749875 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL9749868 | 0.84 | NTRK1 (0.35) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL10649327 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| Hydrochloric Acid SCHEMBL9668992 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10073763 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10914301 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1POLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216345-B1 | QUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-02-19 | — | — | EP | disclosed |
| EP-0216345-A2 | Quinoline derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-04-01 | — | — | EP | disclosed |