Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 13/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745408 | 0.77 | RAB9A (0.68) | KDM4EPOLBTDP1ALDH1A1NPC1 | |
| SCHEMBL6402493 | 0.75 | MEN1 (0.71) | ALDH1A1NPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL1854623 | 0.73 | MAPT (0.54) | KDM4EPOLBTDP1ALDH1A1NPC1 | |
| SCHEMBL27344589 | 0.73 | HPGD (0.58) | AGPAT2KDM4EPOLBTDP1ALDH1A1 | |
| SCHEMBL30640612 | 0.73 | MAPT (0.54) | KDM4EPOLBTDP1ALDH1A1NPC1 | |
| SCHEMBL2499018 | 0.73 | KDM4E (0.66) | KDM4EPOLBTDP1ALDH1A1NPC1 | |
| SCHEMBL31619607 | 0.73 | KDM4E (0.66) | KDM4EPOLBTDP1ALDH1A1NPC1 | |
| SCHEMBL31541259 | 0.73 | MAPT (0.47) | AGPAT2MAPTPKM | |
| SCHEMBL7258809 | 0.72 | AGPAT2 (1.00) | AGPAT2MAPT | |
| SCHEMBL10192052 | 0.72 | NPC1 (0.51) | AGPAT2POLBTDP1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | disclosed |