Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21080659 | 0.91 | PTGS1 (0.45) | KMT2AMAPTMEN1USP2KDM4E | |
| SCHEMBL5440979 | 0.89 | ALDH1A1 (0.42) | KMT2AMAPTMEN1USP2KDM4E | |
| SCHEMBL17835297 | 0.85 | ALDH1A1 (0.43) | KMT2AMAPTMEN1OPRL1ALDH1A1 | |
| SCHEMBL3423304 | 0.85 | OPRL1 (0.38) | KMT2AMAPTMEN1USP2OPRL1 | |
| SCHEMBL3422828 | 0.83 | ALDH1A1 (0.50) | KMT2AUSP2KDM4EPOLBALDH1A1 | |
| SCHEMBL11894038 | 0.82 | MEN1 (0.55) | KMT2AMAPTMEN1USP2KDM4E | |
| SCHEMBL3422049 | 0.82 | KMT2A (0.44) | KMT2AMAPTMEN1KDM4EOPRL1 | |
| SCHEMBL5448789 | 0.81 | ALDH1A1 (0.46) | KMT2AMAPTPOLBOPRL1ALDH1A1 | |
| SCHEMBL3422430 | 0.80 | CYP2C9 (0.47) | KMT2AMAPTPOLBOPRL1ALDH1A1 | |
| SCHEMBL3420466 | 0.80 | CYP2C9 (0.47) | KMT2AMAPTPOLBOPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346339-B1 | BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION | HOECHST CELANESE CORPORATION (US) | 1992-09-09 | — | — | EP | disclosed |
| US-4902784-A | 1,3 Disubstituted-5-diazobarbituric acids | HOECHST CELANESE CORPORATION (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0346339-A1 | BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION. | HOECHST CELANESE CORP (US) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005800-A1 | NOVEL BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION | HOECHST CELANESE CORPORATION (US) | 1989-06-29 | — | — | WO | disclosed |