Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17835297 | 0.91 | ALDH1A1 (0.43) | ALDH1A1TSHROPRL1CYP2C9CYP2C19 | |
| SCHEMBL9749352 | 0.89 | KMT2A (0.43) | ALDH1A1TSHROPRL1KDM4ECYP2C9 | |
| SCHEMBL5448789 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHROPRL1CYP2C9CYP2C19 | |
| SCHEMBL3423304 | 0.81 | OPRL1 (0.38) | ALDH1A1TSHROPRL1CYP2C9CYP2C19 | |
| SCHEMBL21080659 | 0.81 | PTGS1 (0.45) | ALDH1A1TSHRKDM4EMAPTGAA | |
| SCHEMBL3422828 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ECDC25BALOX15 | |
| SCHEMBL30943162 | 0.79 | KDM4E (0.40) | ALDH1A1TSHRKDM4ECYP2C9CYP2C19 | |
| SCHEMBL3422049 | 0.78 | KMT2A (0.44) | ALDH1A1OPRL1KDM4EL3MBTL1MAPT | |
| SCHEMBL3420629 | 0.78 | MAPT (0.49) | ALDH1A1KDM4ETP53L3MBTL1MAPT | |
| SCHEMBL31715766 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| EP-0346339-B1 | BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION | HOECHST CELANESE CORPORATION (US) | 1992-09-09 | — | — | EP | disclosed |
| US-4902784-A | 1,3 Disubstituted-5-diazobarbituric acids | HOECHST CELANESE CORPORATION (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0346339-A1 | BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION. | HOECHST CELANESE CORP (US) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005800-A1 | NOVEL BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION | HOECHST CELANESE CORPORATION (US) | 1989-06-29 | — | — | WO | disclosed |
| US-4735885-A | Deep UV photoresist composition with 1,3-disubstituted-5-diazobarbituric acids | ALLIED CORPORATION (US) | 1988-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | ALDH1A1 83/4885TSHR 4878/4885OPRL1 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.