Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.46 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.46 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.44 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 2/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974953 | 1.00 | PTPN1 (0.48) | PTPN1LGALS3LGALS9LGALS1LGALS7; LGALS7B | |
| SCHEMBL977896 | 1.00 | PTPN1 (0.48) | PTPN1LGALS3LGALS9LGALS1LGALS7; LGALS7B | |
| SCHEMBL977898 | 1.00 | PTPN1 (0.48) | PTPN1LGALS3LGALS9LGALS1LGALS7; LGALS7B | |
| SCHEMBL976416 | 0.93 | PTPN1 (0.48) | PTPN1LGALS3LGALS9LGALS1LGALS7; LGALS7B | |
| SCHEMBL16316511 | 0.92 | PTPN1 (0.51) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL14440519 | 0.92 | PTPN1 (0.50) | PTPN1LGALS3LGALS9LGALS1LGALS7; LGALS7B | |
| SCHEMBL24192988 | 0.91 | ANTXR2 (0.53) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL14199422 | 0.91 | TSHR (0.48) | USP2MEN1POLBKMT2ACA1 | |
| SCHEMBL10700635 | 0.90 | PTPN1 (0.57) | PTPN1LGALS3USP2MEN1POLB | |
| SCHEMBL11232105 | 0.90 | PTPN1 (0.57) | PTPN1LGALS3USP2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720889-B1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LTD (AU) | 2014-11-26 | — | — | EP | disclosed |
| US-8173606-B2 | Sulfated oligosaccharide derivatives | PROGEN PHARMACEUTICALS LIMITED (AU) | 2012-05-08 | — | — | US | disclosed |
| US-20110130354-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LIMITED (AU) | 2011-06-02 | — | — | US | disclosed |
| US-7875592-B2 | inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase; antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment, lowering of blood triglyceride levels and inhibition of cardiovascular disease | PROGEN PHARMACEUTICALS LIMITED (AU) | 2011-01-25 | — | — | US | disclosed |
| US-20070185037-A1 | Sulfated oligosaccharide derivatives | PROGEN INDUSTRIES LIMITED (AU) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185037-A1 | Sulfated oligosaccharide derivatives | HPSE, APOB, LIPG | PTPN1 612/4885LGALS3 116/4885LGALS9 146/4885 |
| US-20110130354-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | HPSE, APOB, LIPG | PTPN1 612/4885LGALS3 116/4885LGALS9 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.