SCHEMBL9749530

SCHEMBL9749530

C=CC(F)c1ccc(S)cc1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4482935 0.78
SCHEMBL9472870 0.76 ESR1 (0.44)
SCHEMBL7113391 0.76 MEN1 (0.38)
SCHEMBL4853724 0.76 CHRNA7 (0.39)
SCHEMBL3322544 0.75 TSHR (0.38)
SCHEMBL13388150 0.73 CYP2C19 (0.36)
SCHEMBL1435360 0.71
SCHEMBL10684990 0.71 HRH3 (0.38) IDO1
SCHEMBL9061872 0.71 IDO1 (0.38) IDO1
SCHEMBL7057745 0.69 LTA4H (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096914-A Hypotensive agents BEIERSDORF AKTIENGESELLSCHAFT (DE) 1992-03-17 US disclosed
US-5028711-A Hypotensive Agents BEIERSDORF AKTIENGESELLSCHAFT (DE) 1991-07-02 US disclosed