Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189812 | 0.82 | MEN1 (0.32) | POLBALDH1A1CYP1A2CYP2A6MEN1 | |
| SCHEMBL12833025 | 0.81 | PSEN1 (0.40) | GABRA1GABRB2POLBHTR1AADRA2A | |
| SCHEMBL20651301 | 0.78 | GABRA1 (0.41) | GABRA1GABRB2POLBSLC6A2HTR2A | |
| SCHEMBL30660375 | 0.78 | ALDH1A1 (0.45) | GABRA1GABRB2POLBHTR1AADRA2A | |
| SCHEMBL2445931 | 0.78 | GABRA1 (0.66) | GABRA1GABRB2POLBLMNASRD5A1 | |
| SCHEMBL1269438 | 0.78 | ALDH1A1 (0.45) | GABRA1GABRB2POLBHTR1AADRA2A | |
| SCHEMBL12833031 | 0.77 | IDO1 (0.48) | GABRA1GABRB2HTR2AHTR2CLMNA | |
| SCHEMBL8257640 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2NPC1RAB9APOLB | |
| SCHEMBL17006146 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2NPC1RAB9APOLB | |
| SCHEMBL28253433 | 0.76 | ELANE (0.38) | GABRA1GABRB2POLBSRD5A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096914-A | Hypotensive agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5028711-A | Hypotensive Agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |