Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.62 |
| ▸ | CES2 | O00748 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076070 | 0.89 | CES2 (0.64) | CES1CES2SMN1; SMN2TSHRCASP1 | |
| SCHEMBL8065539 | 0.86 | SMN1; SMN2 (0.71) | CES1CES2SMN1; SMN2TSHRCASP1 | |
| SCHEMBL29367820 | 0.84 | SMN1; SMN2 (0.55) | CES1CES2SMN1; SMN2TSHRCASP1 | |
| SCHEMBL10631974 | 0.84 | SMN1; SMN2 (0.55) | CES1CES2SMN1; SMN2TSHRCASP1 | |
| SCHEMBL2358618 | 0.84 | SMN1; SMN2 (0.55) | CES1CES2SMN1; SMN2TSHRCASP1 | |
| SCHEMBL522683 | 0.83 | SRD5A2 (0.74) | SMN1; SMN2TSHRCASP1RAB9ANPC1 | |
| SCHEMBL29350361 | 0.83 | SRD5A2 (0.74) | SMN1; SMN2TSHRCASP1RAB9ANPC1 | |
| SCHEMBL11764098 | 0.82 | CES2 (0.58) | CES1CES2SMN1; SMN2TSHRCASP1 | |
| SCHEMBL9648043 | 0.82 | CES2 (0.67) | CES1CES2SMN1; SMN2TSHRCASP1 | |
| SCHEMBL5184941 | 0.82 | SMN1; SMN2 (0.65) | CES1CES2SMN1; SMN2TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248954-B1 | PROCESS FOR REDUCING THE AMOUNT OF DDT-RELATED IMPURITIES IN 1,1-BIS(CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL | ROHM AND HAAS COMPANY (US) | 1992-04-01 | — | — | EP | disclosed |
| EP-0460977-A1 | Process for reducing the amount of DDT-related impurities in 1,1-bis (chlorophenyl)-2,2,2-trichloroethanol | ROHM AND HAAS COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4586996-A | Surface hardner for nylon lens | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1986-05-06 | — | — | US | disclosed |
| US-4009022-A | Selective antagonists for triazine herbicides | ROHM AND HAAS COMPANY (US) | 1977-02-22 | — | — | US | disclosed |