Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473298 | 0.86 | PDCD1LG2 (0.44) | NISCHPDCD1LG2CD274CYP2C19ALDH1A1 | |
| SCHEMBL3919624 | 0.85 | PNMT (0.52) | NISCHPDCD1LG2CD274IDO1TDO2 | |
| SCHEMBL268860 | 0.81 | NISCH (0.44) | NISCHAOC3IDO1TDO2IDO2 | |
| SCHEMBL2474146 | 0.80 | PDCD1LG2 (0.45) | NISCHPDCD1LG2CD274AOC3IDO1 | |
| SCHEMBL31257276 | 0.77 | ADRB2 (0.50) | NISCHAOC3IDO1TDO2IDO2 | |
| SCHEMBL29295702 | 0.77 | ADRB2 (0.42) | NISCHAOC3IDO1TDO2IDO2 | |
| SCHEMBL8995483 | 0.77 | ESR1 (0.41) | PDCD1LG2CD274CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL19332982 | 0.77 | CYP2C19 (0.38) | PDCD1LG2CD274IDO1TDO2CYP2C19 | |
| SCHEMBL9749736 | 0.77 | TSHR (0.42) | PDCD1LG2CD274CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL2328835 | 0.77 | CYP2C19 (0.38) | PDCD1LG2CD274IDO1TDO2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |