SCHEMBL9749757

SCHEMBL9749757

[CH2]CCCCN1C(=O)CCC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.46
MGLL Q99685 3/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.39
HPGD P15428 2/20 0.39
HTT P42858 2/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 1/20 0.36
HTR1A P08908 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTR7 P34969 1/20 0.36
LMNA P02545 2/20 0.36
RAB9A P51151 2/20 0.36
MAPT P10636 2/20 0.36
HSP90AA1 P07900 1/20 0.36
TLR9 Q9NR96 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7881576 0.93 MEN1 (0.44) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8829446 0.87 FAAH (0.53) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8629340 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8632299 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL19233361 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8829438 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8626070 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8862703 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL1982535 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL9652078 0.82 FAAH (0.41) FAAHMGLLMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423105-A1 ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2019-01-09 EP disclosed
US-5108576-A Quantitative analysis OHMICRON CORPORATION (US) 1992-04-28 US disclosed
EP-0436540-A1 PYROELECTRIC THERMOMETRIC DEVICE OHMICRON CORPORATION (US) 1991-07-17 EP disclosed
WO-1989012819-A1 PYROELECTRIC THERMOMETRIC DEVICE OHMICRON CORPORATION (US) 1989-12-28 WO disclosed
US-4340492-A Oil recovery by surfactant waterflooding MOBIL OIL CORPORATION (US) 1982-07-20 US disclosed
US-4124512-A Oil recovery by waterflooding employing succinimido aryl sulfonate surfactants MOBIL OIL CORPORATION (US) 1978-11-07 US disclosed
US-4113632-A ALIPHATIC SUBSTITUTED SUCCINIMIDO ARYL HYDROXY SULFONATE OR ITS SUCCINAMIC ACID DERIVATIVE MOBIL OIL CORPORATION (US) 1978-09-12 US disclosed