Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749387 | 0.83 | LMNA (0.39) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL6232883 | 0.81 | LMNA (0.60) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL9748725 | 0.81 | ALDH1A1 (0.39) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL14045645 | 0.76 | CYP2C9 (0.53) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL15744622 | 0.74 | LMNA (0.53) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL12220331 | 0.74 | CYP2C9 (0.53) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL12588788 | 0.73 | LMNA (0.53) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL5633728 | 0.69 | LMNA (0.49) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL26768564 | 0.69 | LMNA (0.49) | LMNACYP2C9CYP2C19MAPTALOX15 | |
| SCHEMBL9626321 | 0.69 | ALDH1A1 (0.50) | LMNACYP2C9CYP2C19MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346339-B1 | BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION | HOECHST CELANESE CORPORATION (US) | 1992-09-09 | — | — | EP | claimed |
| US-4902784-A | 1,3 Disubstituted-5-diazobarbituric acids | HOECHST CELANESE CORPORATION (US) | 1990-02-20 | — | — | US | claimed |
| EP-0346339-A1 | BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION. | HOECHST CELANESE CORP (US) | 1989-12-20 | — | — | EP | claimed |
| WO-1989005800-A1 | NOVEL BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION | HOECHST CELANESE CORPORATION (US) | 1989-06-29 | — | — | WO | claimed |
| US-4735885-A | Deep UV photoresist composition with 1,3-disubstituted-5-diazobarbituric acids | ALLIED CORPORATION (US) | 1988-04-05 | — | — | US | claimed |
| EP-0346339-B1 | BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION | HOECHST CELANESE CORPORATION (US) | 1992-09-09 | — | — | EP | disclosed |
| US-4902784-A | 1,3 Disubstituted-5-diazobarbituric acids | HOECHST CELANESE CORPORATION (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0346339-A1 | BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION. | HOECHST CELANESE CORP (US) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005800-A1 | NOVEL BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION | HOECHST CELANESE CORPORATION (US) | 1989-06-29 | — | — | WO | disclosed |
| US-4735885-A | Deep UV photoresist composition with 1,3-disubstituted-5-diazobarbituric acids | ALLIED CORPORATION (US) | 1988-04-05 | — | — | US | disclosed |