Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dyrene SCHEMBL4614742 | 0.91 | TSHR (0.60) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL7532886 | 0.87 | TSHR (0.83) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL16113661 | 0.86 | TSHR (0.80) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL6750152 | 0.85 | TSHR (1.00) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL1903290 | 0.85 | TSHR (1.00) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL29364667 | 0.85 | TSHR (1.00) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL8166670 | 0.85 | TSHR (1.00) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL13280 | 0.85 | TSHR (1.00) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL133054 | 0.85 | TSHR (1.00) | TSHRLMNAMAPTKMT2AKDM4E | |
| Dyrene SCHEMBL11055300 | 0.84 | TSHR (0.67) | TSHRMAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100776-A | Forming antigen coupled carrier matrix sensitive to triazine herbicides, immunizing animals to obtain antibodies | DR. PFEIFFER BIOANALYTIK KG (DE) | 1992-03-31 | — | — | US | disclosed |