⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128219 | 0.90 | — | — | |
| SCHEMBL130955 | 0.88 | — | — | |
| SCHEMBL3389113 | 0.88 | SIGMAR1 (0.42) | — | |
| SCHEMBL3389473 | 0.88 | SIGMAR1 (0.42) | — | |
| SCHEMBL22524 | 0.88 | — | — | |
| SCHEMBL866489 | 0.88 | — | — | |
| SCHEMBL3390757 | 0.88 | SIGMAR1 (0.42) | — | |
| SCHEMBL3033549 | 0.88 | SIGMAR1 (0.42) | — | |
| SCHEMBL4809683 | 0.87 | LMNA (0.34) | — | |
| SCHEMBL5678673 | 0.87 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2081 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051819-A1 | PROPIONIC ACID DERIVATIVE AND USE THEREOF IN MEDICINE | 西藏海思科制药有限公司 | 2024-03-14 | — | — | WO | claimed |
| WO-2023222005-A1 | AROMATIC HETEROCYCLIC COMPOUND AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海翊石医药科技有限公司 | 2023-11-23 | — | — | WO | claimed |
| CN-116848094-A | Tertiary amine lipid compounds and uses thereof | 华南理工大学 | 2023-10-03 | — | — | CN | claimed |
| CN-116535460-A | Sulfur-containing peptidomimetic compounds, and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-08-04 | — | — | CN | claimed |
| WO-2023125184-A1 | TERTIARY AMINE LIPID COMPOUND AND USE THEREOF | 华南理工大学 | 2023-07-06 | — | — | WO | claimed |
| CN-116209664-A | Small molecule modulators of IL-17 | 利奥制药有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-111233786-B | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-11-26 | — | — | CN | claimed |
| CN-113135896-A | Methylpyrazole derivatives as RET inhibitors | 正大天晴药业集团股份有限公司 | 2021-07-20 | — | — | CN | claimed |
| WO-2021031071-A1 | AMIDE DERIVATIVE AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2021-02-25 | — | — | WO | claimed |
| CN-111233786-A | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-06-05 | — | — | CN | claimed |
| EP-0045155-B1 | GUANIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-02 | — | — | EP | claimed |
| US-4451463-A | HISTAMINE ANTAGONIST, INHIBITOR OF GASTRIC ACID SECRETION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-29 | — | — | US | claimed |
| US-4447441-A | ANTIHISTAMINE, ANTIULCER AND ANTISECRETORY AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-08 | — | — | US | claimed |
| US-4362728-A | Haloguanidine compounds, pharmaceutical compositions and methods of use | ICI AMERICAS INC. (US) | 1982-12-07 | — | — | US | claimed |
| EP-0065823-A1 | Heterocyclic guanidines as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | claimed |
| EP-0061318-A2 | Guanidinoheterocyclic derivatives as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-29 | — | — | EP | claimed |
| EP-0060697-A1 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060094-A2 | Guanidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| EP-0059597-A2 | Guanidino-substituted heterocyclic derivatives having histamine H-2 antagonist activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-08 | — | — | EP | claimed |
| EP-0030092-A1 | Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-06-10 | — | — | EP | claimed |