Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28387947 | 0.84 | GAA (0.56) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL7799415 | 0.80 | KDM4E (0.54) | GAAKDM4EALDH1A1LMNAGLA | |
| SCHEMBL12269180 | 0.78 | NPC1 (0.49) | GAAKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL12248480 | 0.78 | MAOB (0.50) | GAAALDH1A1MAOBCA12CA9 | |
| SCHEMBL6654083 | 0.77 | KDM4E (0.43) | GAAKDM4EALDH1A1LMNAGLA | |
| SCHEMBL1391086 | 0.77 | KDM4E (0.54) | GAAKDM4EALDH1A1LMNAGLA | |
| SCHEMBL4792814 | 0.76 | NPC1 (0.47) | GAAMAOBCA12CA9CA1 | |
| SCHEMBL12248485 | 0.76 | CYP2A6 (0.50) | GAAALDH1A1LMNAMAOBCA12 | |
| SCHEMBL12248487 | 0.76 | ALOX5 (0.56) | GAAKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12938181 | 0.75 | ACHE (0.59) | GAANPC1MGAMSIPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |