SCHEMBL9750040

SCHEMBL9750040

CN(C)c1ccc(C(=CC(O)C=C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HPGD P15428 3/20 0.48
MAPT P10636 2/20 0.48
TSHR P16473 3/20 0.47
ALOX15 P16050 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP3A4 P08684 1/20 0.47
HBB P68871 1/20 0.47
HSD17B10 Q99714 1/20 0.46
APP P05067 1/20 0.44
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 2/20 0.43
TDP1 Q9NUW8 1/20 0.42
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
TLR9 Q9NR96 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9749604 0.88 CNR2 (0.42) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL8747387 0.85 ALDH1A1 (0.50) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL7615901 0.80 ALDH1A1 (0.45) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL10453227 0.80 ALDH1A1 (0.45) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL9749967 0.79 ALDH1A1 (0.46) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL4905210 0.79 ALDH1A1 (0.44) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL9815915 0.78 ALDH1A1 (0.56) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL6937372 0.78 ALDH1A1 (0.56) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL9084475 0.74 APP (0.53) ALDH1A1MAPTALOX15HBBAPP
SCHEMBL9840374 0.74 ALDH1A1 (0.41) ALDH1A1HPGDMAPTTSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63254166-A None JP disclosed
US-5084593-A Cyanine, aniline dyes for heat sensitive recording elements RICOH COMPANY, LTD. (JP) 1992-01-28 US disclosed
US-5057154-A Colorfastness, stability RICOH COMPANY, LTD. (JP) 1991-10-15 US disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed
US-4939117-A Leuco dyes and recording material employing the same RICOH COMPANY, LTD. (JP) 1990-07-03 US disclosed
JP-S63254166-A NOVEL LEUCO DYE AND RECORDING MATERIAL CONTAINING SAME RICOH CO LTD 1988-10-20 JP disclosed