SCHEMBL6937372

SCHEMBL6937372

CC=C(c1ccc(N(C)C)cc1)c1ccc(N(C)C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
HPGD P15428 3/20 0.56
MAPT P10636 3/20 0.56
ALOX15 P16050 4/20 0.55
TSHR P16473 3/20 0.55
HSD17B10 Q99714 2/20 0.55
MAPK1 P28482 3/20 0.54
CYP3A4 P08684 2/20 0.54
HBB P68871 1/20 0.54
RAB9A P51151 4/20 0.48
NPC1 O15118 4/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
GFER P55789 1/20 0.45
APP P05067 2/20 0.45
SLC2A1 P11166 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2A13 Q16696 1/20 0.44
TP53 P04637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17811469 0.88 RAB9A (0.48) ALDH1A1HPGDMAPTALOX15TSHR
SCHEMBL10473228 0.86 MAOB (0.56) ALDH1A1HPGDMAPTTSHRHSD17B10
SCHEMBL10473229 0.86 MAOB (0.56) ALDH1A1HPGDMAPTTSHRHSD17B10
SCHEMBL9815915 0.85 ALDH1A1 (0.56) ALDH1A1HPGDMAPTALOX15TSHR
SCHEMBL8269356 0.81 ALDH1A1 (0.52) ALDH1A1HPGDMAPTALOX15TSHR
SCHEMBL4897408 0.81 ALDH1A1 (0.52) ALDH1A1HPGDMAPTALOX15TSHR
SCHEMBL10680528 0.81 ALDH1A1 (0.47) ALDH1A1HPGDMAPTALOX15TSHR
SCHEMBL10680536 0.81 ALDH1A1 (0.47) ALDH1A1HPGDMAPTALOX15TSHR
SCHEMBL8747387 0.79 ALDH1A1 (0.50) ALDH1A1HPGDMAPTALOX15TSHR
SCHEMBL26754991 0.78 ALDH1A1 (0.54) ALDH1A1HPGDMAPTALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed
US-4898941-A Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-02-06 US disclosed
EP-0127203-B1 NEW PHTHALIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND RECORDING SYSTEM UTILIZING THE SAME AS COLOURLESS CHROMOGENIC MATERIAL KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1989-06-28 EP disclosed
US-4770973-A READABLE BY OPTICAL DEVICES AND FIXED BY LIGHT Kanzaki Paper Manufacturing Limited (JP) 1988-09-13 US disclosed
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed
US-4281855-A Pressure-sensitive or heat-sensitive recording material and novel 2,2-diarylchromeno compounds used therein CIBA-GEIGY CORPORATION (US) 1981-08-04 US disclosed
US-4187233-A Pressure-sensitive or heat-sensitive recording material and novel 2,2-diarylchromeno compounds used therein CIBA-GEIGY CORPORATION (US) 1980-02-05 US disclosed
US-4055430-A Light sensitive material containing an ethylene compound dye former, an organic polymer compound containing chlorine and a plasticizer FUJI PHOTO FILM CO., LTD. (JA) 1977-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 ALDH1A1 2369/4885HPGD 3594/4885MAPT 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.