Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937998 | 0.74 | CA12 (0.39) | ALDH1A1HSD17B10CA12CA9CYP1A2 | |
| Indole SCHEMBL29065921 | 0.73 | TRPA1 (0.47) | ALDH1A1HSD17B10CA12CA9CYP1A2 | |
| SCHEMBL28847307 | 0.70 | CYP1A2 (0.44) | ALDH1A1HIF1ACYP1B1HSD17B10CA12 | |
| SCHEMBL8680691 | 0.67 | ALDH1A1 (0.48) | ALDH1A1HIF1ACYP1B1HSD17B10CA12 | |
| SCHEMBL4853659 | 0.66 | ALDH1A1 (0.72) | ALDH1A1HIF1ACYP1B1HSD17B10CA9 | |
| SCHEMBL23664 | 0.66 | ALDH1A1 (0.72) | ALDH1A1HIF1ACYP1B1HSD17B10CA9 | |
| SCHEMBL4848746 | 0.66 | ALDH1A1 (0.72) | ALDH1A1HIF1ACYP1B1HSD17B10CA9 | |
| SCHEMBL29532882 | 0.66 | ALDH1A1 (0.72) | ALDH1A1HIF1ACYP1B1HSD17B10CA9 | |
| SCHEMBL6545915 | 0.65 | ALDH1A1 (0.44) | ALDH1A1HIF1ACYP1B1HSD17B10CA9 | |
| SCHEMBL8743449 | 0.65 | ALDH1A1 (0.44) | ALDH1A1HIF1ACYP1B1HSD17B10ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872079-B2 | Naphthoxazine composition | SEKISUI CHEMICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090240006-A1 | A curable mixture of a naphthazine compound having a terminal aromatic ring bearing an hydroxyl group and a epoxy resins; high heat resistance; hardness; tensile strength;mechanical strength; dimensional stability; moldings; electronics; spacecraft; aircraft;automobile parts | CASE WESTERN RESERVE UNIVERSITY (US) | 2009-09-24 | — | — | US | disclosed |