Dimethylamine

Dimethylamine

SCHEMBL9750075

CNC.O=C(c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.63
SRD5A2 P31213 2/20 0.63
CES2 O00748 1/20 0.63
CES1 P23141 1/20 0.63
ALDH1A1 P00352 2/20 0.58
MAPK1 P28482 1/20 0.57
HPGD P15428 2/20 0.55
PTGS2 P35354 2/20 0.55
MAPK13 O15264 1/20 0.53
MAPK12 P53778 1/20 0.53
MAPK11 Q15759 1/20 0.53
MAPK14 Q16539 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9442387 0.91 SRD5A2 (0.74) NR4A1SRD5A2CES2CES1ALDH1A1
SCHEMBL50462 0.91 SRD5A2 (0.74) NR4A1SRD5A2CES2CES1ALDH1A1
Acetone SCHEMBL29156010 0.89 SRD5A2 (0.65) NR4A1SRD5A2CES2CES1ALDH1A1
Bicarbonate SCHEMBL9817101 0.89 SRD5A2 (0.71) NR4A1SRD5A2CES2CES1ALDH1A1
Hydrochloric Acid SCHEMBL4594202 0.89 SRD5A2 (0.71) NR4A1SRD5A2CES2CES1ALDH1A1
Hydrochloric Acid SCHEMBL4594201 0.89 SRD5A2 (0.71) NR4A1SRD5A2CES2CES1ALDH1A1
Benzophenone SCHEMBL28328302 0.87 ALDH1A1 (0.78) SRD5A2CES2CES1ALDH1A1MAPK1
Benzophenone SCHEMBL28325902 0.87 ALDH1A1 (0.78) SRD5A2CES2CES1ALDH1A1MAPK1
Benzophenone SCHEMBL329684 0.87 ALDH1A1 (0.78) SRD5A2CES2CES1ALDH1A1MAPK1
SCHEMBL9483032 0.86 CES2 (0.64) NR4A1SRD5A2CES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5084593-A Cyanine, aniline dyes for heat sensitive recording elements RICOH COMPANY, LTD. (JP) 1992-01-28 US disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed