Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750417 | 0.89 | MAPT (0.42) | NPC1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL9750097 | 0.89 | ALDH1A1 (0.40) | NPC1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL9749572 | 0.88 | ALDH1A1 (0.45) | NPC1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL9838423 | 0.88 | MAPT (0.41) | NPC1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL9749985 | 0.84 | ALDH1A1 (0.39) | NPC1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL9750060 | 0.84 | RAB9A (0.43) | NPC1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL9749968 | 0.84 | MAPT (0.47) | NPC1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL9749972 | 0.83 | KMT2A (0.46) | NPC1MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9750137 | 0.83 | ALDH1A1 (0.44) | NPC1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL9750005 | 0.82 | MEN1 (0.45) | NPC1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5057154-A | Colorfastness, stability | RICOH COMPANY, LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4939117-A | Leuco dyes and recording material employing the same | RICOH COMPANY, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |