Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70048 | 0.85 | NFKB1 (0.57) | KDM4EHPGDHSD17B10USP2NFKB1 | |
| SCHEMBL308253 | 0.84 | KDM4E (0.69) | KDM4EHPGDHSD17B10USP2PTPN1 | |
| SCHEMBL28802807 | 0.82 | NFKB1 (0.55) | KDM4EHPGDHSD17B10USP2NFKB1 | |
| Hydrochloric Acid SCHEMBL11595983 | 0.82 | NFKB1 (0.55) | KDM4EHPGDHSD17B10USP2NFKB1 | |
| Hydrochloric Acid SCHEMBL6335114 | 0.82 | KDM4E (0.67) | KDM4EHPGDHSD17B10USP2SMN1; SMN2 | |
| SCHEMBL6904018 | 0.82 | KDM4E (0.52) | KDM4EHPGDHSD17B10USP2NFKB1 | |
| SCHEMBL6890851 | 0.79 | KDM4E (0.68) | KDM4EHPGDHSD17B10USP2ALOX15 | |
| SCHEMBL3154080 | 0.79 | KDM4E (1.00) | KDM4EHPGDHSD17B10USP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6343159 | 0.77 | KDM4E (0.61) | KDM4EHPGDHSD17B10USP2PTPN1 | |
| SCHEMBL21686414 | 0.77 | BRD4 (0.47) | KDM4EHPGDHSD17B10USP2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515395-A1 | SAPPHYRINS, DERIVATIVES AND SYNTHESIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991009861-A1 | SAPPHYRINS, DERIVATIVES AND SYNTHESIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-07-11 | — | — | WO | disclosed |