SCHEMBL70048

SCHEMBL70048

O=C(O)c1ccc(C(=O)O)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.57
ALOX15 P16050 1/20 0.57
BLM P54132 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
KDM4E B2RXH2 4/20 0.52
HPGD P15428 4/20 0.52
HSD17B10 Q99714 4/20 0.52
USP2 O75604 1/20 0.52
HCAR2 Q8TDS4 1/20 0.46
DAO P14920 4/20 0.44
MAPT P10636 1/20 0.44
SRD5A2 P31213 1/20 0.44
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
PIN1 Q13526 2/20 0.41
SMAD3 P84022 1/20 0.41
CYP2C19 P33261 3/20 0.41
GPR35 Q9HC97 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11595983 0.97 NFKB1 (0.55) NFKB1ALOX15BLMSMN1; SMN2KDM4E
SCHEMBL28802807 0.97 NFKB1 (0.55) NFKB1ALOX15BLMSMN1; SMN2KDM4E
SCHEMBL17195442 0.87 KDM4E (0.48) NFKB1ALOX15BLMSMN1; SMN2KDM4E
SCHEMBL9750144 0.85 KDM4E (0.63) NFKB1ALOX15BLMSMN1; SMN2KDM4E
SCHEMBL5173538 0.83
SCHEMBL4729088 0.83
SCHEMBL20894303 0.83 NFKB1 (0.43) NFKB1ALOX15BLMSMN1; SMN2KDM4E
SCHEMBL5171513 0.81
SCHEMBL10848882 0.81
SCHEMBL20929042 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115670-A1 A METHOD FOR PREPARING SUPPORTED MOF MEMBRANES INDUCED BY LOW-CRYSTAL AGGREGATED STATE STRUCTURES, MOF MEMBRANES AND THEIR APPLICATIONS NANJING UNIVERSITY OF TECHNOLOGY (CN) 2026-04-30 US claimed
US-12576386-B2 Aluminum-based metal-organic framework having three dimensional porous structure and comprising at least two types of ligands, preparation method therefor, and use thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-03-17 US claimed
US-20250360468-A1 SEPARATION MEMBRANE COMPLEX AND METHOD OF PRODUCING SEPARATION MEMBRANE COMPLEX NGK INSULATORS, LTD. (JP) 2025-11-27 US claimed
CN-115642364-B High-adhesion lithium ion battery diaphragm and preparation method thereof 江苏厚生新能源科技股份有限公司 2025-02-18 CN claimed
CN-119350645-A Preparation method and application of micron-sized GM-1 material 南京师范大学 2025-01-24 CN claimed
CN-119221048-A Anti-warping additive, electrolytic copper foil bath solution, copper foil, preparation method and application thereof 吉和昌新材料(荆门)有限公司 2024-12-31 CN claimed
WO-2024190041-A1 SEPARATION MEMBRANE COMPOSITE BODY AND METHOD FOR PRODUCING SEPARATION MEMBRANE COMPOSITE BODY 日本碍子株式会社 2024-09-19 WO claimed
CN-118047816-A Fluorine-containing iron-based metal organic framework material, preparation method and application 中国科学院大连化学物理研究所 2024-05-17 CN claimed
CN-117700778-A Preparation method of hydrophobic metal organic framework material particles 中国辐射防护研究院 2024-03-15 CN claimed
CN-117701281-A Metal-organic framework and fluoride nanocrystalline composite photon functional material and preparation method thereof 浙江大学杭州国际科创中心 2024-03-15 CN claimed
CN-103073480-B A kind of preparation method of the carboxylic acid of 2 penta [c] pyrroles of (tertbutyloxycarbonyl) octahydro ring 5 武汉药明康德新药开发有限公司 2017-08-29 CN claimed
US-9714320-B2 Process for preparing a high molecular weight heteroaromatic polyester or copolyester UHDE INVENTA-FISCHER GMBH (DE) 2017-07-25 US claimed
EP-2814864-A2 PROCESS FOR PREPARING A HIGH MOLECULAR WEIGHT HETEROAROMATIC POLYESTER OR COPOLYESTER Uhde Inventa-Fischer GmbH (DE) 2014-12-24 EP claimed
US-20140357808-A1 Process For Preparing A High Molecular Weight Heteroaromatic Polyester Or Coplyester UHDE INVENTA-FISCHER GMBH (DE) 2014-12-04 US claimed
US-8653048-B2 Prodrugs based on gemcitabine structure and synthetic methods and applications thereof SANLUGEN PHARMATECH LTD. (CN) 2014-02-18 US claimed
WO-2013120989-A2 PROCESS FOR PREPARING A HIGH MOLECULAR WEIGHT HETEROAROMATIC POLYESTER OR COPOLYESTER UHDE INVENTA-FISCHER GMBH (DE) 2013-08-22 WO claimed
CN-102428093-A Prodrugs based on gemcitabine structure as well as synthetic method and application thereof SANLUGEN PHARMATECH LTD 2012-04-25 CN claimed
US-20120088908-A1 Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof SANLUGEN PHARMATECH LTD. (CN) 2012-04-12 US claimed
EP-2423215-A1 PRODRUGS BASED ON GEMCITABINE STRUCTURE AS WELL AS SYNTHETIC METHOD AND APPLICATION THEREOF Sanlugen Pharmatech Ltd. (CN) 2012-02-29 EP claimed
US-5308861-A Tetrapyrole compounds NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1994-05-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088908-A1 Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof TYMP, DCTD, GLS2 NFKB1 2429/4885ALOX15 2359/4885BLM 918/4885
US-12576386-B2 Aluminum-based metal-organic framework having three dimensional porous structure and comprising at least two types of ligands, preparation method therefor, and use thereof ALAD, SLC38A7, SLC5A11 NFKB1 501/4885ALOX15 41/4885BLM 1484/4885
US-20260115670-A1 A METHOD FOR PREPARING SUPPORTED MOF MEMBRANES INDUCED BY LOW-CRYSTAL AGGREGATED STATE STRUCTURES, MOF MEMBRANES AND THEIR APPLICATIONS AP2M1, PICALM, AP1M1 NFKB1 1132/4885ALOX15 94/4885BLM 3534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.