Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749697 | 0.94 | MAPT (0.41) | MAPTMEN1KMT2ACNR2KDM4E | |
| SCHEMBL9749956 | 0.89 | MAPT (0.40) | MAPTMEN1KMT2ACNR2KDM4E | |
| SCHEMBL9749975 | 0.88 | ALDH1A1 (0.47) | MAPTMEN1KMT2AAGTR1KDM4E | |
| SCHEMBL9750124 | 0.87 | CNR2 (0.40) | MAPTMEN1KMT2ACNR2KDM4E | |
| SCHEMBL9749968 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9749549 | 0.81 | MAPT (0.38) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9750055 | 0.77 | MAPT (0.38) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9840314 | 0.76 | ALDH1A1 (0.47) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9749664 | 0.76 | KMT2A (0.41) | MAPTMEN1KMT2ACNR2KDM4E | |
| SCHEMBL9749572 | 0.75 | ALDH1A1 (0.45) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |