Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750392 | 0.94 | MAPT (0.39) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9749968 | 0.87 | MAPT (0.47) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL9749549 | 0.85 | MAPT (0.38) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9749956 | 0.84 | MAPT (0.40) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9750055 | 0.82 | MAPT (0.38) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9749975 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9750124 | 0.81 | CNR2 (0.40) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9840314 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9749664 | 0.80 | KMT2A (0.41) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9750036 | 0.76 | MAPT (0.44) | MAPTALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5057154-A | Colorfastness, stability | RICOH COMPANY, LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4939117-A | Leuco dyes and recording material employing the same | RICOH COMPANY, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |