Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 4/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 4/20 | 0.37 |
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
| ▸ | LCT | P09848 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389100 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1RARBAOC3GPR88 | |
| SCHEMBL28515552 | 0.84 | LMNA (0.39) | KDM4EALDH1A1AOC3GPR88MEN1 | |
| SCHEMBL10618772 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL4850677 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28706904 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29211021 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28403155 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9750029 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10430492 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28903655 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315912-B1 | SEBOSUPPRESSIVE PREPARATIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-06-17 | — | — | EP | disclosed |
| EP-0315912-A1 | Sebosuppressive preparations | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-05-17 | — | — | EP | disclosed |