Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073163 | 0.78 | KDM4E (0.38) | POLBP2RY2HTR2AKDM4EALDH1A1 | |
| SCHEMBL11184478 | 0.75 | KDM4E (0.38) | LMNAPOLBP2RY2HTR2AKDM4E | |
| SCHEMBL11194965 | 0.75 | KDM4E (0.38) | LMNAPOLBP2RY2HTR2AKDM4E | |
| SCHEMBL11710445 | 0.73 | ATM (0.44) | LMNAPOLBP2RY2HTR2AKDM4E | |
| SCHEMBL7658701 | 0.73 | KDM4E (0.38) | LMNAPOLBP2RY2HTR2AKDM4E | |
| SCHEMBL9398200 | 0.73 | HDAC3 (0.59) | LMNAPOLB | |
| SCHEMBL3056750 | 0.71 | ALDH1A1 (0.39) | POLBP2RY2KDM4EALDH1A1 | |
| SCHEMBL9090427 | 0.70 | HTR2A (0.40) | ABATLMNAHTR2AKDM4EMAPT | |
| SCHEMBL27570925 | 0.69 | ABAT (0.34) | ABATHTR2AITGB3ITGB1ITGAV | |
| SCHEMBL8797292 | 0.69 | HTR2A (0.43) | LMNAPOLBHTR2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212569-B1 | THIATION PROCESS | ETHYL CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |