Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797292 | 0.86 | HTR2A (0.43) | KDM4EALDH1A1POLBHTR2AEDNRA | |
| SCHEMBL11184478 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1POLBHTR2ACYP2D6 | |
| SCHEMBL11194965 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1POLBHTR2ACYP2D6 | |
| SCHEMBL11710445 | 0.84 | ATM (0.44) | KDM4EALDH1A1POLBHTR2ACYP2D6 | |
| SCHEMBL7658701 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1POLBHTR2ACYP2D6 | |
| SCHEMBL3056750 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1POLBCYP2D6ATM | |
| SCHEMBL129881 | 0.79 | CYP2D6 (0.44) | KDM4EALDH1A1POLBHTR2AEDNRA | |
| SCHEMBL31379445 | 0.79 | CYP2D6 (0.44) | KDM4EALDH1A1POLBHTR2AEDNRA | |
| SCHEMBL9750458 | 0.78 | ABAT (0.39) | KDM4EALDH1A1POLBHTR2AP2RY2 | |
| SCHEMBL6014069 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1POLBHTR2AEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332881-B | Preparation method of thioester derivative | 大连理工常熟研究院有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116332881-A | Preparation method of thioester derivative | 大连理工常熟研究院有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-122036588-A | Drug design strategy for releasing hydrogen sulfide based on enzymolysis thiocarbonyl and application of drug design strategy in indole mother nucleus drug modification | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-122036573-A | Drug design strategy for releasing hydrogen sulfide based on enzymolysis thiocarbonyl and application of drug design strategy in diclofenac-like drug modification | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-122036574-A | Drug design strategy for releasing hydrogen sulfide based on enzymolysis thiocarbonyl and application of drug design strategy in modification of terminal carboxylic acid drug | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| US-12552890-B2 | Chiral azobenzene polymer crosslinked thin film and preparation method therefor and application thereof | SOOCHOW UNIVERSITY (CN) | 2026-02-17 | — | — | US | disclosed |
| CN-119490441-A | Prodrug design strategy for releasing hydrogen sulfide based on direct esterase hydrolysis thiocarboxylic acid and application of prodrug design strategy in modification of carboxylic acid drugs | 中国药科大学 | 2025-02-21 | — | — | CN | disclosed |
| US-20240294684-A1 | CHIRAL AZOBENZENE POLYMER CROSSLINKED THIN FILM AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2024-09-05 | — | — | US | disclosed |
| CN-116332881-B | Preparation method of thioester derivative | 大连理工常熟研究院有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116332881-A | Preparation method of thioester derivative | 大连理工常熟研究院有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112409616-A | Chiral azobenzene polymer crosslinked film and preparation method and application thereof | 苏州大学 | 2021-02-26 | — | — | CN | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| US-5807813-A | Lubricating oil composition | IDEMITSU KOSAN CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0783032-A1 | LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-07-09 | — | — | EP | disclosed |
| EP-0240212-B1 | PREPARATION OF HIGHLY PURE ALPHA-METHYLSTYRENE POLYMER | THE DOW CHEMICAL COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4748222-A | Preparation of highly pure alpha-methylstyrene polymer | THE DOW CHEMICAL COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0058217-B1 | A PROCESS FOR PRODUCING A RANDOM COPOLYMER AND RANDOM COPOLYMER | PHILLIPS PETROLEUM COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4368327-A | REACTION OF CORRESPONDING FURANONE WITH SALT OF THIOCARBOXYLIC ACID | CIBA-GEIGY CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |
| EP-0058217-A1 | A process for producing a random copolymer and random copolymer | PHILLIPS PETROLEUM COMPANY (US) | 1982-08-25 | — | — | EP | disclosed |
| US-4277591-A | ORGANOLITHIUM INITIATOR AND AN ORGANIC COMPOUND OF SODIUM, POTASSIUM, RUBIDIUM, OR CESIUM | PHILLIPS PETROLEUM COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552890-B2 | Chiral azobenzene polymer crosslinked thin film and preparation method therefor and application thereof | LIMA1, SMCHD1, CDH1 | KDM4E 786/4885ALDH1A1 970/4885POLB 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.