Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ILK | Q13418 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20027965 | 0.82 | TSHR (0.58) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL7794327 | 0.81 | TSHR (0.61) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL9296047 | 0.79 | TSHR (0.58) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL7516781 | 0.79 | TSHR (0.58) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL9332640 | 0.76 | TSHR (0.55) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL9332630 | 0.75 | TSHR (0.54) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL31299616 | 0.74 | TSHR (0.53) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL7794805 | 0.73 | TSHR (0.78) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL28802104 | 0.73 | TSHR (0.52) | TSHRILKALDH1A1MAPTHTT | |
| SCHEMBL6815148 | 0.71 | ILK (0.61) | TSHRILKALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |