⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627221 | 0.98 | KDM4E (0.35) | — | |
| SCHEMBL9627422 | 0.80 | — | — | |
| SCHEMBL845581 | 0.78 | — | — | |
| SCHEMBL3114383 | 0.76 | KDM4E (0.42) | — | |
| SCHEMBL3335220 | 0.74 | — | — | |
| SCHEMBL13485367 | 0.74 | — | — | |
| SCHEMBL691912 | 0.74 | — | — | |
| SCHEMBL13610798 | 0.74 | KDM4E (0.33) | — | |
| SCHEMBL9627220 | 0.74 | NPSR1 (0.45) | — | |
| SCHEMBL19385549 | 0.71 | NNMT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |