Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527765 | 0.83 | TSHR (0.42) | ILKTSHRALDH1A1CYP1A2KDM4E | |
| SCHEMBL2022385 | 0.82 | TSHR (0.44) | ILKTSHRALDH1A1CYP1A2KDM4E | |
| SCHEMBL3333926 | 0.81 | ALDH1A1 (0.50) | ILKTSHRALDH1A1CYP1A2KDM4E | |
| SCHEMBL1249727 | 0.81 | TSHR (0.43) | ILKTSHRALDH1A1CYP1A2KDM4E | |
| SCHEMBL691044 | 0.81 | ALDH1A1 (0.47) | ILKTSHRALDH1A1CYP1A2KDM4E | |
| SCHEMBL9627220 | 0.80 | NPSR1 (0.45) | ALDH1A1KDM4EHSD17B10HPGDPKM | |
| SCHEMBL3334719 | 0.79 | TSHR (0.42) | ILKTSHRALDH1A1CYP1A2KDM4E | |
| SCHEMBL1179173 | 0.79 | ALDH1A1 (0.49) | TSHRALDH1A1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL3330523 | 0.78 | ALDH1A1 (0.44) | ILKTSHRALDH1A1CYP1A2KDM4E | |
| SCHEMBL2825669 | 0.78 | TSHR (0.44) | ILKTSHRALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |