Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27766706 | 0.90 | KDM4E (0.50) | ALDH1A1CYP1A2HSD17B10GAAKMT2A | |
| SCHEMBL31575 | 0.84 | KDM4E (0.58) | ALDH1A1CYP1A2HSD17B10GAAKMT2A | |
| SCHEMBL2022385 | 0.84 | TSHR (0.44) | ALDH1A1CYP1A2HSD17B10GAAKMT2A | |
| SCHEMBL3330523 | 0.83 | ALDH1A1 (0.44) | ALDH1A1CYP1A2HSD17B10GAAKMT2A | |
| SCHEMBL691044 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HSD17B10KMT2AKDM4E | |
| SCHEMBL1249727 | 0.82 | TSHR (0.43) | ALDH1A1CYP1A2HSD17B10KMT2AKDM4E | |
| SCHEMBL29706037 | 0.82 | CDC7 (0.47) | ALDH1A1CYP1A2HSD17B10GAAKMT2A | |
| SCHEMBL19940202 | 0.81 | HSD17B10 (0.46) | ALDH1A1CYP1A2HSD17B10GAAKMT2A | |
| SCHEMBL3334719 | 0.81 | TSHR (0.42) | ALDH1A1CYP1A2HSD17B10KMT2AKDM4E | |
| SCHEMBL4297707 | 0.81 | ALDH1A1 (0.45) | ALDH1A1CYP1A2HSD17B10GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384204-B | Enol silicon ether compound, preparation method and application thereof | 康龙化成手性医药技术(宁波)有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-117384204-A | Enol silicon ether compound, preparation method and application thereof | 康龙化成手性医药技术(宁波)有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117362316-A | Synthesis method of tetrahydropyrrolothiazole compound | 康龙化成手性医药技术(宁波)有限公司 | 2024-01-09 | — | — | CN | disclosed |
| EP-2699617-A1 | CONJUGATED POLYMERS | Merck Patent GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| US-8344154-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2013-01-01 | — | — | US | disclosed |
| WO-2012143081-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
| US-20100145063-A1 | 2- thioethenyl substituted carbapenem derivatives | MARUYAMA TAKAHISA | 2010-06-10 | — | — | US | disclosed |
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-20090029939-A1 | Pre-organized tricyclic integrase inhibitor compounds | GILEAD SCIENCES, INC. | 2009-01-29 | — | — | US | disclosed |
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
| EP-1870412-A1 | 2-THIOETHENYL CARBAPENEM DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2007-12-26 | — | — | EP | disclosed |
| US-7253180-B2 | Pre-organized tricyclic integrase inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253180-B2 | Pre-organized tricyclic integrase inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029939-A1 | Pre-organized tricyclic integrase inhibitor compounds | MUS81, CDKL4, INTS6 | ALDH1A1 1902/4885CYP1A2 330/4885HSD17B10 1543/4885 |
| US-20100145063-A1 | 2- thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, TPMT | ALDH1A1 1218/4885CYP1A2 1068/4885HSD17B10 939/4885 |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, BPGM | ALDH1A1 1182/4885CYP1A2 1120/4885HSD17B10 554/4885 |
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | ALDH1A1 2788/4885CYP1A2 4127/4885HSD17B10 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.