Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15015409 | 0.89 | DDB1 (0.40) | MEN1KMT2ADDAH1NOS1DDB1 | |
| SCHEMBL12949506 | 0.89 | MAOA (0.53) | MEN1KMT2ADDAH1NOS1DDB1 | |
| SCHEMBL4673092 | 0.87 | DDB1 (0.41) | MEN1KMT2ADDAH1NOS1DDB1 | |
| SCHEMBL4670744 | 0.85 | MEN1 (0.45) | MEN1KMT2ADDAH1NOS1DDB1 | |
| Hydrochloric Acid SCHEMBL5269331 | 0.83 | MEN1 (0.44) | MEN1KMT2ADDAH1NOS1DDB1 | |
| SCHEMBL12676793 | 0.82 | CARM1 (0.43) | MEN1KMT2ADDAH1NOS1DDB1 | |
| SCHEMBL8111506 | 0.79 | HRH3 (0.38) | MEN1KMT2ADDAH1NOS1DDB1 | |
| SCHEMBL27648678 | 0.76 | KMT2A (0.38) | KMT2ADDB1CRBNLMNACARM1 | |
| SCHEMBL12110641 | 0.74 | CARM1 (0.50) | DDB1CRBNMAOAMAOBMAPT | |
| SCHEMBL23295277 | 0.70 | MAOA (0.65) | MEN1KMT2ADDB1CRBNMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |