Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115653 | 0.89 | KMT2A (0.51) | GAATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL122191 | 0.86 | NR4A3 (0.51) | GAATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL9005761 | 0.85 | NR4A3 (0.44) | GAATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL4411084 | 0.85 | NR4A3 (0.50) | GAATSHRALDH1A1HSD17B10KDM4E | |
| Potassium Ion SCHEMBL3239020 | 0.84 | NR4A3 (0.43) | GAATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL10598773 | 0.78 | KMT2A (0.45) | ALDH1A1KDM4EMAPK1SMN1; SMN2MAPT | |
| SCHEMBL10599000 | 0.77 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2MAPTNR4A3 | |
| SCHEMBL9005800 | 0.76 | MAPT (0.51) | GAATSHRALDH1A1HSD17B10MAPK1 | |
| SCHEMBL1419628 | 0.75 | GPR35 (0.53) | GAATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL10596793 | 0.75 | KMT2A (0.45) | GAAALDH1A1MAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003068-A | Pyridazinone manufacture | MONSANTO COMPANY (US) | 1991-03-26 | — | — | US | claimed |
| EP-0127313-B1 | THE PRODUCTION OF HAPLOID SEED, OF DOUBLED HAPLOIDS AND OF HOMOZYGOUS PLANT LINES THEREFROM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1989-07-19 | — | — | EP | disclosed |