SCHEMBL9750767

SCHEMBL9750767

CC(C)(C)c1ccc(C2C=CC(c3ccccc3)(C(C)(C)C)C=C2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.35
TNKS O95271 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
PARP3 Q9Y6F1 1/20 0.34
HSD11B1 P28845 2/20 0.32
GRIN2B Q13224 2/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ICMT O60725 1/20 0.31
NR1I2 O75469 1/20 0.31
RORC P51449 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 2/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
MAOA P21397 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3423873 0.84 KDM1A (0.42) KDM1ARORCTSHRMAPTMEN1
SCHEMBL2687211 0.81
SCHEMBL2348824 0.74
SCHEMBL5622784 0.69 KDM1A (0.32) KDM1AMAOA
SCHEMBL9341653 0.68 MEN1 (0.35) KDM1AALDH1A1MAPTMEN1KMT2A
SCHEMBL4327374 0.64 KDM1A (0.41) KDM1ATNKSTNKS2PARP3SLC6A2
SCHEMBL1577842 0.62 HTR2A (0.41) KDM1ATSHRMEN1KMT2AMAOA
Tert-Butylbenzene SCHEMBL337648 0.61 MAPK1 (0.55) ALDH1A1TSHRMAPTKMT2ATDP1
Tert-Butylbenzene SCHEMBL22264597 0.61 MAPK1 (0.55) ALDH1A1TSHRMAPTKMT2ATDP1
Tert-Butylbenzene SCHEMBL22264599 0.61 MAPK1 (0.55) ALDH1A1TSHRMAPTKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068407-A OXIDATION OF TERTIARY-ALKYL SUBSTITUTED AROMATICS MONSANTO COMPANY (US) 1991-11-26 US disclosed