SCHEMBL5622784

SCHEMBL5622784

CC(C)(C)C1(C(C)(C)C)C=CC(c2ccccc2)C=C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.32
MAOA P21397 4/20 0.32
MAOB P27338 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7511837 0.76 KDM1A (0.40) KDM1AMAOAMAOB
SCHEMBL1577842 0.76 HTR2A (0.41) KDM1AMAOAMAOB
SCHEMBL7427186 0.74 KDM1A (0.39) KDM1AMAOAMAOB
SCHEMBL7077759 0.72 KDM1A (0.38) KDM1AMAOAMAOB
SCHEMBL7199456 0.72 CHRNA7 (0.41) KDM1AMAOAMAOB
SCHEMBL2390258 0.71 HTR2C (0.32) KDM1AMAOAMAOB
SCHEMBL1074533 0.71 KDM1A (0.40) KDM1AMAOAMAOB
SCHEMBL7985531 0.71 HTR2C (0.32) KDM1AMAOAMAOB
SCHEMBL222998 0.71 CHRNA7 (0.35) KDM1AMAOAMAOB
SCHEMBL3625731 0.71 CYP2C19 (0.35) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10166530-B2 Use of certain transition metal hyperaccumulator plants for reducing organic compounds in a green manner CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2019-01-01 US disclosed
EP-3177399-A1 USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER CNRS (Centre National de la Recherche Scientifique) (FR) 2017-06-14 EP disclosed
US-20170157594-A1 USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2017-06-08 US disclosed
WO-2016009116-A1 USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2016-01-21 WO disclosed
US-7208614-B2 Method for producing, via organometallic compounds, organic intermediate products ARCHIMICA GMBH (DE) 2007-04-24 US disclosed
US-20050001333-A1 Method for producing, via organometallic compounds, organic intermediate products ARCHIMICA GMBH (DE) 2005-01-06 US disclosed
US-20040251563-A1 Method for poducing, via organometallic compounds, organic intermediate products EUTICALS GMBH (DE) 2004-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10166530-B2 Use of certain transition metal hyperaccumulator plants for reducing organic compounds in a green manner SLC39A3, OAT, GLB1 KDM1A 3026/4885MAOA 367/4885MAOB 291/4885
US-20170157594-A1 USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER SLC39A3, OAT, GLB1 KDM1A 3026/4885MAOA 367/4885MAOB 291/4885
US-20050001333-A1 Method for producing, via organometallic compounds, organic intermediate products NISCH, HDHD5, TYR KDM1A 3222/4885MAOA 230/4885MAOB 171/4885
US-20040251563-A1 Method for poducing, via organometallic compounds, organic intermediate products ROS1, AOC3, NOX4 KDM1A 718/4885MAOA 465/4885MAOB 484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.