Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721920 | 0.75 | TP53 (0.57) | LPAR1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL708221 | 0.75 | LPAR1 (0.76) | LPAR1LPAR2LPAR5 | |
| SCHEMBL13349602 | 0.75 | ACKR3 (0.67) | ACHEBCHELPAR1L3MBTL1MAPK1 | |
| SCHEMBL7273776 | 0.75 | L3MBTL1 (0.59) | ACHEBCHELPAR1MEN1KMT2A | |
| SCHEMBL714380 | 0.74 | LPAR1 (0.72) | LPAR1LPAR2LPAR5 | |
| SCHEMBL708598 | 0.74 | LPAR1 (0.84) | LPAR1LPAR2LPAR5 | |
| SCHEMBL706715 | 0.74 | LPAR1 (0.72) | LPAR1LPAR2LPAR5 | |
| SCHEMBL19438511 | 0.72 | LPAR1 (0.62) | LPAR1L3MBTL1MAPK1ALDH1A1LMNA | |
| SCHEMBL13890982 | 0.72 | ACKR3 (0.77) | ALDH1A1ACKR3 | |
| SCHEMBL708091 | 0.72 | LPAR1 (0.69) | LPAR1LPAR2LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988735-A | Ethylene diamine active cardiovascular therapy | SIMES (IT) | 1991-01-29 | — | — | US | disclosed |