Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751050 | 0.76 | KDM4E (0.42) | KDM4EALOX15MMP1MMP2MMP3 | |
| SCHEMBL6681598 | 0.66 | ANPEP (0.42) | ANPEPFNTAFNTBMEN1KMT2A | |
| SCHEMBL27768608 | 0.66 | ANPEP (0.42) | ANPEPFNTAFNTBMEN1KMT2A | |
| SCHEMBL29245840 | 0.64 | KDM4E (0.39) | KDM4EALOX15ALDH1A1FNTAFNTB | |
| SCHEMBL9082541 | 0.63 | LMNA (0.43) | ALDH1A1POLBANPEPFNTAFNTB | |
| SCHEMBL27974645 | 0.62 | FNTA (0.48) | KDM4EALOX15ALDH1A1MAPK1FNTA | |
| SCHEMBL18584318 | 0.62 | GAA (0.39) | KDM4EALOX15MMP1MMP2MMP3 | |
| SCHEMBL9081277 | 0.62 | NPC1 (0.42) | KDM4EALDH1A1ANPEPMEN1KMT2A | |
| SCHEMBL9751048 | 0.62 | KDM4E (0.33) | KDM4EALOX15MMP1MMP2MMP3 | |
| SCHEMBL29759479 | 0.62 | KDM4E (0.43) | KDM4EALOX15ALDH1A1POLBFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347435-A4 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | — | 1991-11-21 | — | — | EP | disclosed |
| WO-1989001940-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-03-09 | — | — | WO | disclosed |