Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | CTSG | P08311 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417559 | 1.00 | NR1H2 (0.46) | NR1H2NR1H3GPR84BIDMCL1 | |
| SCHEMBL504060 | 0.99 | NR1H2 (0.43) | NR1H2NR1H3GPR84BIDMCL1 | |
| SCHEMBL9568063 | 0.81 | PTPRC (0.39) | KDM4ECA12USP2CA1CA2 | |
| SCHEMBL529430 | 0.79 | CA12 (0.43) | KDM4ECA12USP2CA1CA2 | |
| SCHEMBL3806455 | 0.77 | PTGER4 (0.47) | PPARAKDM4ECA12USP2CA1 | |
| SCHEMBL13440433 | 0.75 | CA12 (0.46) | KDM4ECA12USP2CA1CA2 | |
| SCHEMBL2288532 | 0.75 | KMT2A (0.38) | GPR84ELANEKDM4ECA12USP2 | |
| SCHEMBL14958500 | 0.73 | CA12 (0.39) | KDM4ECA12USP2CA1CA2 | |
| SCHEMBL14799943 | 0.72 | BID (0.46) | NR1H2NR1H3BIDMCL1PPARA | |
| SCHEMBL3807234 | 0.72 | CA12 (0.46) | MCL1KDM4ECA12USP2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400075-A4 | ENHANCEMENT OF THE THERAPEUTIC PROPERTIES OF GLYCOPROTEIN | — | 1991-07-03 | — | — | EP | disclosed |
| EP-0400075-A1 | ENHANCEMENT OF THE THERAPEUTIC PROPERTIES OF GLYCOPROTEIN | GENZYME CORPORATION (US) | 1990-12-05 | — | — | EP | disclosed |
| WO-1989007641-A1 | ENHANCEMENT OF THE THERAPEUTIC PROPERTIES OF GLYCOPROTEIN | GENZYME CORPORATION (US) | 1989-08-24 | — | — | WO | disclosed |