SCHEMBL529430

SCHEMBL529430

NCCc1cccc2c1S(=O)(=O)NC2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.43
CA9 Q16790 3/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
BCHE P06276 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
KMT2A Q03164 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
TAAR1 Q96RJ0 7/20 0.40
PDE7A Q13946 2/20 0.35
PDE7B Q9NP56 1/20 0.35
HMGB1 P09429 1/20 0.35
ADRA2C P18825 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3806455 0.81 PTGER4 (0.47) CA12CA9CA1CA2CA7
SCHEMBL504060 0.80 NR1H2 (0.43) CA12CA9CA1CA2CA7
SCHEMBL13440433 0.80 CA12 (0.46) CA12CA9CA1CA2CA7
SCHEMBL3417559 0.79 NR1H2 (0.46) CA12CA9CA1CA2CA7
SCHEMBL9751229 0.79 NR1H2 (0.46) CA12CA9CA1CA2CA7
SCHEMBL14958500 0.78 CA12 (0.39) CA12CA9CA1CA2CA7
SCHEMBL3807234 0.76 CA12 (0.46) CA12CA9CA1CA2CA7
SCHEMBL82972 0.76 GABRA1 (0.45) CA12CA9CA1CA2CA7
SCHEMBL193750 0.74 CA12 (0.50) CA12CA9CA1CA2CA7
SCHEMBL1463156 0.74 CA9 (0.50) CA12CA9CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11845810-B2 Silicon glycan and method of preparing same DOW SILICONES CORPORATION (US) 2023-12-19 US disclosed
US-20220395447-A1 PERSONAL CARE COMPOSITION COMPRISING A SILICON GLYCAN ROHM AND HAAS COMPANY 2022-12-15 US disclosed
EP-4061854-A1 SILICON GLYCAN AND METHOD OF PREPARING SAME Dow Silicones Corporation (US) 2022-09-28 EP disclosed
EP-3906262-A1 SILICON GLYCAN AND METHOD OF PREPARING SAME Dow Silicones Corporation (US) 2021-11-10 EP disclosed
WO-2021118775-A1 PERSONAL CARE COMPOSITION COMPRISING A SILICON GLYCAN ROHM AND HAAS COMPANY (US) 2021-06-17 WO disclosed
WO-2021101677-A1 SILICON GLYCAN AND METHOD OF PREPARING SAME DOW SILICONES CORPORTION (US) 2021-05-27 WO disclosed
WO-2021101679-A1 METHOD OF PREPARING A SILICON GLYCAN DOW SILICONES CORPORATION (US) 2021-05-27 WO disclosed
WO-2020142344-A1 SILICON GLYCAN AND METHOD OF PREPARING SAME DOW SILICONES CORPORATION (US) 2020-07-09 WO disclosed
EP-2391218-B1 CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY SMARTCELLS INC (US) 2020-03-18 EP disclosed
US-10398781-B2 Conjugate based systems for controlled drug delivery SMARTCELLS, INC. (US) 2019-09-03 US disclosed
EP-2598171-A2 DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO Smartcells, Inc. (US) 2013-06-05 EP disclosed
EP-2598170-A2 DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO Smartcells, Inc. (US) 2013-06-05 EP disclosed
US-20130131310-A1 DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO SMARTCELLS, INC. 2013-05-23 US disclosed
WO-2012015681-A2 DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO SMARTCELLS, INC. (US) 2012-02-02 WO disclosed
WO-2012015687-A2 DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO SMARTCELLS, INC. (US) 2012-02-02 WO disclosed
US-20110301083-A1 CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY SMARTCELLS, INC. 2011-12-08 US disclosed
EP-2391646-A1 CRYSTALLINE INSULIN-CONJUGATES Smartcells, Inc. (US) 2011-12-07 EP disclosed
US-20110281791-A1 CRYSTALLINE INSULIN-CONJUGATES SMARTCELLS, INC. 2011-11-17 US disclosed
WO-2010088294-A1 CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY SMARTCELLS, INC. (US) 2010-08-05 WO disclosed
WO-2010088300-A1 CRYSTALLINE INSULIN-CONJUGATES SMARTCELLS, INC. (US) 2010-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10398781-B2 Conjugate based systems for controlled drug delivery SI, CSGALNACT1, CD44 CA12 98/4885CA9 263/4885CA1 357/4885
US-20110301083-A1 CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY SI, CSGALNACT1, CD44 CA12 98/4885CA9 263/4885CA1 357/4885
US-20110281791-A1 CRYSTALLINE INSULIN-CONJUGATES IAPP, INSR, GPR119 CA12 470/4885CA9 651/4885CA1 1911/4885
US-20130131310-A1 DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO ALK, ABL1, ERBB3 CA12 2345/4885CA9 1347/4885CA1 3296/4885
US-20220395447-A1 PERSONAL CARE COMPOSITION COMPRISING A SILICON GLYCAN CUTA, SCLY, YWHAZ CA12 986/4885CA9 976/4885CA1 2910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.