Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751238 | 0.87 | MIF (0.39) | CA1CA2ALDH1A1KMT2ANPC1 | |
| SCHEMBL9751232 | 0.86 | NPC1 (0.48) | CA1CA2ALDH1A1LMNAKMT2A | |
| SCHEMBL9751301 | 0.81 | CA12 (0.41) | CA1CA2ALDH1A1LMNAPOLB | |
| SCHEMBL9751216 | 0.80 | CA1 (0.48) | CA1CA2ALDH1A1LMNAKMT2A | |
| SCHEMBL9327324 | 0.80 | ALDH1A1 (0.46) | PPARGPPARAALDH1A1LMNAKMT2A | |
| SCHEMBL9325985 | 0.78 | CA1 (0.43) | CA1CA2ALDH1A1LMNAKMT2A | |
| SCHEMBL9327057 | 0.78 | CA1 (0.49) | CA1CA2ALDH1A1LMNAKMT2A | |
| SCHEMBL9326044 | 0.77 | CA1 (0.51) | CA1CA2ALDH1A1LMNAKMT2A | |
| SCHEMBL9751322 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1LMNAKMT2ANPC1POLB | |
| SCHEMBL9751164 | 0.76 | MEN1 (0.41) | ALDH1A1LMNAKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1146887-A | — | — | None | — | — | JP | disclosed |
| US-5006515-A | Immunology disorders, antitumor agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| JP-H01146887-A | PHOSPHORUS-CONTAINING 2-ISOXAZOLINE AND ISOXAZOLE | HOECHST AG | 1989-06-08 | — | — | JP | disclosed |