Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751270 | 0.87 | MME (0.43) | MMEACEECE1CA1CA2 | |
| SCHEMBL9327057 | 0.71 | CA1 (0.49) | CA1CA2LMNAMEN1KMT2A | |
| SCHEMBL9326044 | 0.69 | CA1 (0.51) | CA1CA2LMNAMEN1KMT2A | |
| SCHEMBL9751233 | 0.68 | CA1 (0.43) | CA1CA2LMNAMEN1KMT2A | |
| SCHEMBL31244593 | 0.68 | ALDH1A1 (0.51) | LMNAMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL10581518 | 0.67 | ALDH1A1 (0.54) | LMNAMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL7695939 | 0.66 | ALDH1A1 (0.66) | CA1CA2LMNAMEN1KMT2A | |
| SCHEMBL31353721 | 0.66 | ALDH1A1 (0.56) | LMNATSHRMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8053510 | 0.65 | ALDH1A1 (0.63) | CA1CA2LMNAMEN1KMT2A | |
| SCHEMBL14642447 | 0.65 | MIF (0.78) | KMT2AMIFHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006515-A | Immunology disorders, antitumor agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |