Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16424736 | 0.81 | PDK2 (0.58) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL29967490 | 0.78 | ESR1 (0.50) | PDK2ALDH1A1CYP3A4TSHRRECQL | |
| SCHEMBL2837959 | 0.78 | ESR1 (0.50) | PDK2ALDH1A1CYP3A4TSHRRECQL | |
| SCHEMBL19147675 | 0.75 | PDK2 (0.58) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL15642760 | 0.75 | ALDH1A1 (0.55) | PDK2ALDH1A1CYP3A4TSHRRECQL | |
| SCHEMBL17816711 | 0.73 | PDK2 (0.56) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL16424869 | 0.72 | PDK2 (0.52) | PDK2ALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL22243479 | 0.71 | PDK2 (0.60) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL24401623 | 0.71 | PDK2 (0.51) | PDK2TSHRRECQLESR1ESR2 | |
| SCHEMBL20687361 | 0.71 | PDK2 (0.46) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407523-A1 | OPTICAL DEVICES HAVING LAYERS OF LOW MOLECULAR WEIGHT ORGANIC MATERIALS AND METHODS FOR MAKING. | EASTMAN KODAK CO (US) | 1991-01-16 | — | — | EP | disclosed |