Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751346 | 0.95 | MEN1 (0.48) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10667115 | 0.89 | MEN1 (0.52) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9751312 | 0.84 | MEN1 (0.41) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL8321859 | 0.84 | MEN1 (0.46) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10809942 | 0.80 | RAF1 (0.45) | ALDH1A1TLR8TLR7SCN9A | |
| SCHEMBL9751309 | 0.80 | TDP1 (0.70) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL31118332 | 0.80 | ALDH1A1 (0.49) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10668736 | 0.80 | TDP1 (0.64) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL8382590 | 0.79 | MEN1 (0.47) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL6290662 | 0.78 | MEN1 (0.72) | MEN1TTRPPOXKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992089-A | Pre- and postemergence | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0228788-B1 | HERBICIDAL DERIVATIVES OF SUBSTITUTED BENZOYL-HYDRAZINIUM COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-27 | — | — | EP | disclosed |