SCHEMBL9751392

SCHEMBL9751392

O=C1CCSN1C(=O)Nc1cccc(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.59
ALDH1A1 P00352 4/20 0.59
GAA P10253 2/20 0.59
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
RECQL P46063 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
LMNA P02545 2/20 0.50
HTT P42858 2/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
TSHR P16473 2/20 0.46
HPGD P15428 1/20 0.46
KDM4E B2RXH2 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
FADS1 O60427 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9751426 0.82 MEN1 (0.52) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL7556321 0.76 MAPT (0.63) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL20236118 0.73 MEN1 (0.76) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL28273734 0.73 MEN1 (0.88) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL9771474 0.72 KMT2A (0.57) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL11559130 0.72 ALDH1A1 (0.51) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL9751424 0.71 MAPT (0.56) MAPTGAAKMT2ANPC1RAB9A
SCHEMBL11641875 0.71 NPSR1 (1.00) MAPTALDH1A1MEN1KMT2ARECQL
SCHEMBL6178671 0.70 KMT2A (0.62) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL12476809 0.70 MEN1 (0.97) MAPTALDH1A1MEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5008150-A Hydrophilic colloid, amine salt or quarternary ammonium, ester of p-hydroxybenzoic acid; improved adhesion MITSUBISHI PAPER MILLS LIMITED (JP) 1991-04-16 US disclosed